The pancreas : an integrated textbook of basic science, medicine, and surgery. Fourth edition.

種類:

電子ブック

責任表示:

edited by Hans G. Beger, Markus W. Büchler, Ralph H. Hruban, Julia Mayerle, John P. Neoptolemos, Tooru Shimosegawa, Andrew L. Warshaw, David C. Whitcomb, Yupei Zhao ; coordinating editor, Christiane Groß.

出版情報:

Hoboken, NJ : John Wiley & Sons, Inc., 2023.

著者名:

Beger, H. G.

Büchler, Markus, 1955-

Hruban, Ralph H.

Mayerle, Julia

Neoptolemos, John

Shimosegawa, Tooru

Warshaw, Andrew L.

Whitcomb, David C.

Zhao, Yupei

Gross, Christiane

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ISBN:

9781119876007 [1119876001] (: electronic bk)    

注記:

Includes bibliographical references and index.
"The fourth edition of The Pancreas presents the most comprehensive and latest knowledge about the genetic and molecular biological basis of embryology, anatomy, physiology, pathophysiology, and pathology for all disorders of the pancreas. Compared to the first edition, published in 1998, the fourth edition contains three newly addressed diseases of the pancreas: autoimmune pancreatitis, benign and premalignant cystic neoplasms, and neuroendocrine tumors. The understanding of the functions and dysfunctions of the exocrine and endocrine pancreas is derived from increasingly profound molecular biological data on the actions of compounds in subcellular compartments and intracellular transcription pathways. In the respective chapters, the presentation of the inflammatory (acute or chronic) and oncological diseases (benign, premalignant, or advanced cancer) is based on molecular biological understanding of pathomorphological processes and clinical phenomena.
In clinical pancreatology, new and improved technical devices enable the gastroenterologist and the gastrointestinal surgeon to identify lesions by high-resolution imaging techniques, imaging of metabolic processes, and intrapancreatic ductal morphologic processes. The molecular profiling of pancreatic ductal adenocarcinoma has provided a deeper understanding of the genomic alterations that drive pancreatic ductal adenocarcinoma, including driver genes, actionable mutations, copy number alterations, patterns of genomic aberrations, structural variations, and mutational signatures. These findings have transformed our biological genomic understanding, but are still of limited clinical utility. Significant progress has been made in understanding the molecular pathogenesis of pancreatic cancer and identification of various molecular subtypes.
However, this improved understanding has unfortunately not yet led to relevant progress for the patient's cure, although survival gain after radical cancer resection in addition with adjuvant chemotherapy is significant for selected groups of patients"--
Description based on online resource; title from digital title page (viewed on August 09, 2023).
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岐阜大学構成員専用E-BOOKS (Gifu University members only)