Protein-Nanoparticle Interactions : The Bio-Nano Interface. 1st ed. 2013

種類:

電子ブック

責任表示:

by Masoud Rahman, Sophie Laurent, Nancy Tawil, L'Hocine Yahia, Morteza Mahmoudi

出版情報:

Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013

著者名:

Rahman, Masoud.

Laurent, Sophie.

Tawil, Nancy.

Yahia, L'Hocine.

Mahmoudi, Morteza.

SpringerLink (Online service)

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シリーズ名:

Springer Series in Biophysics ; 15

ISBN:

9783642375552 [3642375553]    

注記:

The Biological Significance of ‘Nano’ interactions -- Nanoparticle and Protein Corona -- Protein Corona: Applications and Challenges -- Analytical Methods for Corona Evaluations.
In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the impo

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