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Optical Interferometry for Biology and Medicine. 1st ed. 2012

種類:
電子ブック
責任表示:
by David D. Nolte
出版情報:
New York, NY : Springer New York : Imprint: Springer, 2012
著者名:
シリーズ名:
Bioanalysis, Advanced Materials, Methods, and Devices ; 1
ISBN:
9781461408901 [1461408903]  CiNii Books  Calil
注記:
Part I. Fundamentals of Biological Optics -- CHAPTER 1. INTERFEROMETRY -- CHAPTER 2. DIFFRACTION AND LIGHT SCATTERIN -- CHAPTER 3. SPECKLE AND SPATIAL COHERENCE -- CHAPTER 4. SURFACE OPTICS -- Part II. Molecular Interferometry and Biosensors -- CHAPTER 5. INTERFEROMETRIC THIN FILM OPTICAL BIOSENSORS -- CHAPTER 6. DIFFRACTIONBASED INTERFEROMETRIC BIOSENSORS -- CHAPTER 7. INTERFEROMETRIC WAVEGUIDE SENSORS -- Part III. Cellular Interferometry -- CHAPTER 8. CELL STRUCTURE AND DYNAMICS -- CHAPTER 9. INTERFERENCE MICROSCOPY -- Part IV. Interferometry of Biological Tissues -- CHAPTER 10. LIGHT PROPAGATION IN TISSUE -- CHAPTER 11. OPTICAL COHERENCE TOMOGRAPHY -- CHAPTER 12. HOLOGRAPHY OF TISSUES -- CHAPTER 13. APPENDIX: MATHEMATICAL FORMULAS.
This book presents the fundamental physics of optical interferometry as applied to biophysical, biological and medical research. Interference is at the core of many types of optical detection and is a powerful probe of cellular and tissue structure in interfererence microscopy and in optical coherence tomography. It is also the root cause of speckle and other imaging artefacts that limit range and resolution. For biosensor applications, the inherent sensitivity of interferometry enables ultrasensitive detection of molecules in biological samples for medical diagnostics. In this book, emphasis is placed on the physics of light scattering, beginning with the molecular origins of refraction as light propagates through matter, and then treating the stochastic nature of random fields that ultimately dominate optical imaging in cells and tissue. The physics of partial coherence plays a central role in the text, with a focus on coherence detection techniques that allow information to be selectively detected out of i
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