Contemporary Biostatistics with Biopharmaceutical Applications. 1st ed. 2019

種類:

電子ブック

責任表示:

edited by Lanju Zhang, Ding-Geng (Din) Chen, Hongmei Jiang, Gang Li, Hui Quan

出版情報:

Cham : Springer International Publishing : Imprint: Springer, 2019

著者名:

Zhang, Lanju.

Chen, Ding-Geng (Din).

Jiang, Hongmei.

Li, Gang.

Quan, Hui.

SpringerLink (Online service)

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シリーズ名:

ICSA Book Series in Statistics ;

ISBN:

9783030153106 [303015310X]    

注記:

Part I Biostatistical Methodology -- Dimension Reduction in High Dimensional Multivariate Time Series Analysis -- Multi-Panel Kendall Plot Applied to Measuring Dependence -- Flexible Optimal Design Strategies -- A Multivariate Spatial Modelling Approach with Nonparametric Cross-covariogram -- A Deterministic Global Optimization Method for Variational Inference -- Part II Statistical Genetics and Bioinformatics -- Subgroup identification with latent Dirichlet allocation -- Dictionary learning based genotype imputation to improve power for association testing -- Integrating Transcriptional Time Lag Information into Gene Regulatory Network Construction -- Optimal experimental designs for fMRI when the model matrix is uncertain -- On Exact and Approximate Distributions of K-homopolymer for iid and Markov Dependent DNA Sequences -- Part III Regulatory Statistics -- Utilizing Seamless Adaptive Designs for NASH Clinical Trials -- A Bayesian Non-inferiority Design with Companion Constancy Test in Active Controlled Tr
This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications. Featuring contributions presented at the 2017 ICSA Applied Statistics Symposium held in Chicago, IL on June 25 to 28, 2017, this book explores timely topics that have a high potential impact on statistical methodology and future research in biostatistics and biopharmaceuticals. The theme of this conference was Statistics for A New Generation: Challenges and Opportunities, in recognition of the advent of a new generation of statisticians. The conference attracted statisticians working in academia, government, and industry; domestic and international statisticians. From the conference, the editors selected 28 high-quality presentations and invited the speakers to prepare full chapters for this book. These contributions are divided into four parts: Part I Biostatistical Methodology, Part II Statistical Genetics and Bioinformatics, Part III Regulatory Statistics, and Part IV Biopharmaceutical Research an

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