Epigenetics, Brain and Behavior. 1st ed. 2012
- 種類:
- 電子ブック
- 責任表示:
- edited by Paolo Sassone Corsi, Yves Christen
- 出版情報:
- Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012
- 著者名:
- シリーズ名:
- Research and Perspectives in Neurosciences ;
- ISBN:
- 9783642279133 [3642279139]
- 注記:
- What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone variants, microRNA metabolic pathways and non-histone proteins modifications. Thus, while neuronal plasticity is rightly thought to be intimately associated to genomic control, it is critical to appreciate that there is much more to the genome than DNA sequence. Recent years have seen spectacular advances in the field of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigenetic regulation to brain functions has been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molecular mechanisms implica
- ローカル注記:
- 学内専用E-BOOKS (local access only)
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