Immunotoxicity, Immune Dysfunction, and Chronic Disease. 1st ed. 2012

種類:

電子ブック

責任表示:

edited by Rodney R. Dietert, Robert W. Luebke

出版情報:

Totowa, NJ : Humana Press : Imprint: Humana, 2012

著者名:

• Dietert, Rodney R.
• Luebke, Robert W.
• SpringerLink (Online service)

シリーズ名:

Molecular and Integrative Toxicology ;

ISBN:

9781617798122 [1617798126]    

注記:

Introduction to Immunotoxicity -- The Environment-Immune Route to Chronic Disease -- Asthma and Respiratory Allergies -- Cutaneous Allergies -- Food Allergies -- Factors Involved in Onset of Type1 Diabetes -- Rheumatoid Arthritis -- Environment, Immune Dysfunction and Systemic Lupus Erythematosus -- Multiple Sclerosis, Alzheimer’s Disease and Inflammation: A Hypothetical View -- Immune Dysfunction in Autism Spectrum Disorders -- Atherosclerosis and Inflammatory Heart Disease -- Inflammatory Bowel Disease and Celiac Disease: Environmental Risks Factors and Consequences -- COPD and Other Inflammatory Diseases of the Lung: Focus on AhR signaling -- Environment, the Immune System, and Depression: An Integrative Review and Discussion of the Infection-Defense Hypothesis -- Cancer – Childhood Acute Leukemia -- Environmental Toxicants and Susceptibility to Infection -- Reducing the Prevalence of Immune-Based Chronic Disease.
Immunotoxicity, Immune Dysfunction, and Chronic Disease is among the first books to illustrate the linkage between environmental risk factors (e.g., chemicals, drugs, diet, lifestyles), environmentally-induced immune dysfunction and the full range of resulting chronic diseases and conditions. There is a detailed discussion of specific immune-based chronic diseases and conditions that emerge in children and adults and affect different physiological systems. The book integrates a consideration of risk factors and specific immunotoxic alterations with disease outcomes. A significant number of diseases and conditions are discussed, such as systemic allergic diseases affecting the lung, skin and gastrointestinal tract, systemic autoimmune diseases (type 1 diabetes,multiple sclerosis and lupus) and chronic conditions that are not traditionally associated with chemically-mediated immunomodulation (depression, frailty, and atherosclerosis). Inflammatory dysregulation is a common thread that connects many of the disea

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