Naturally Occurring Antibodies (NAbs). 1st ed. 2012

種類:

電子ブック

責任表示:

edited by Hans U. Lutz

出版情報:

New York, NY : Springer New York : Imprint: Springer, 2012

著者名:

• Lutz, Hans U.
• SpringerLink (Online service)

シリーズ名:

Advances in Experimental Medicine and Biology ; 750

ISBN:

9781461434610 [1461434610]    

注記:

Naturally Occurring IgM Antibodies to Oxidation‑Specific Epitopes -- Naturally Occurring Autoantibodies to Apoptotic Cells -- Naturally Occurring Antibodies Directed against Carbohydrate Tumor Antigens -- Naturally Occurring Antibodies as Therapeutics for Neurologic Disease: Can Human Monoclonal IgMs Replace the Limited Resource IVIG? -- Nature and Nurture of Catalytic Antibodies -- Naturally Occurring Autoantibodies in Mediating Clearance of Senescent Red Blood Cells -- Naturally Occurring Autoantibodies against b‑Amyloid -- Multi‑Faceted Role of Naturally Occurring Autoantibodies in Fighting Pathogens -- Immunoregulation by Naturally Occurring and Disease‑Associated Autoantibodies: Binding to Cytokines and their Role in Regulation of T‑Cell Responses -- Modulation of Dendritic Cells and Regulatory T Cells by Naturally Occurring Antibodies -- Control of B Cells Expressing Naturally Occurring Autoantibodies -- Granulocyte Death Regulation by Naturally Occurring Autoantibodies -- Naturally Occurring Autoantibo
This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.

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