The Eukaryotic Replisome: a Guide to Protein Structure and Function. 1st ed. 2012

種類:

電子ブック

責任表示:

edited by Stuart MacNeill

出版情報:

Dordrecht : Springer Netherlands : Imprint: Springer, 2012

著者名:

• MacNeill, Stuart.
• SpringerLink (Online service)

シリーズ名:

Subcellular Biochemistry ; 62

ISBN:

9789400745728 [9400745729]    

注記:

Successful chromosome replication is vital for maintaining the integrity of the genetic material in all forms of cellular life. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular mechanisms of genome duplication vital for future advances in diagnosis and treatment. Inspired by recent exciting breakthroughs in protein structure determination and written by leading experts in the field, The Eukaryotic Replisome: a guide to protein structure and function takes the reader on a guided journey through the intricate molecular machinery of eukaryotic chromosomal DNA replication, from replication origin recognition and the assembly of the pre-replicative complexes in G1 through to the final processing of Okazaki fragments at the end of S-phase. This extensively illustrated book is an invaluable source of information, ideas and inspiration for all those with an interest in chromosome replication, wh

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