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Synaptic Plasticity : Dynamics, Development and Disease. 1st ed. 2012

種類:
電子ブック
責任表示:
edited by Michael R. Kreutz, Carlo Sala
出版情報:
Vienna : Springer Vienna : Imprint: Springer, 2012
著者名:
ISBN:
9783709109328 [3709109329]  CiNii Books  Calil
注記:
Preface Michael R. Kreutz, Carlo Sala -- Molecular organization of the pre- and postsynaptic scaffold: 1. Uli Thomas, Stephan Sigrist: Glutamate receptors in synaptic assembly and plasticity – case studies on fly NMJs -- 2. Chiara Verpelli, Michael J. Schmeisser, Carlo Sala, Tobias M. Boeckers: Scaffold proteins at the Postsynaptic Density -- 3. Laurent Fagni: Diversity of metabotropic glutamate receptor interacting proteins and patho-physiological functions -- 4. Peter Penzes, Igor Rafalovich: Regulation of the actin cytoskeleton in dendritic spines -- 5. Olena Bukalo, Alexander Dityatev: Synaptic cell adhesion molecules -- Molecular dynamics of the synapse: 6. Shigeo Okabe: Molecular dynamics of excitatory synapses -- 7. Renato Frischknecht, Eckart D. Gundelfinger: The brain's extracellular matrix and its role in synaptic plasticity -- 8. Robert van den Berg, Casper C. Hoogenraad: Molecular motors in cargo trafficking and synapse assembly -- 9. Martin Heine: Surface traffic in synaptic membranes -- 10. Bong
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for
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