Cell Signaling & Molecular Targets in Cancer. 1st ed. 2012

種類:

電子ブック

責任表示:

edited by Malay Chatterjee, Khosrow Kashfi

出版情報:

New York, NY : Springer New York : Imprint: Springer, 2012

著者名:

• Chatterjee, Malay.
• Kashfi, Khosrow.
• SpringerLink (Online service)

ISBN:

9781461407300 [1461407303]    

注記:

Acknowledgement -- GRB2 Signaling as a Molecular Target for Cancer -- Human arylamine N-acetyltransferase 1 : from drug metabolism to drug target -- Targeting Argininosuccinate Synthetase in Cancer Therapy -- Parathyroid hormone-related peptide signaling in cancer -- Signaling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma -- Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract -- AIB1: A Transcriptional Coactivator which Integrates Signaling Crosstalk in Cancer Cells -- Rational Design of DNA Anti-cancer Agent that Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy -- Estrogen Receptor Signaling in Lung Cancer -- Microparticle Dissemination of Biological Activities: Implications for Cancer Biology -- Protein Kinase D Signaling in Cancer -- Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer,Reactive Oxygen Species and Antioxidants -- PPARg, Thiazolidinediones, Lung Cancer -- Targeting Signal Transd
The abnormal behavior of all cancer cells regardless of cancer type is irregular cell signaling pathway activity. A mechanistic approach dealing with a fundamental and molecular view based signaling cascade are exciting and dynamic areas of cancer research. This book illuminates what we know, how we know and what remains to be discovered in this regard. The book explore and identify not only the key compounds of cell signaling pathway but also the interaction between them, the cross-talk. This book bring together up-to-date summaries of the signaling components that are likely to be used in diagnosis, prognosis and novel target for pharmaceutical intervention and therapeutic development and highlight the importance of molecular approach to clinical cancer research. A lot clinical trials and outcome are promising. The translation of recent advance in the knowledge of intracellular signaling into the generation of innovative molecular targeted cancer therapy are essential features of this book. Goals are manifo

ローカル注記:

学内専用E-BOOKS (local access only)