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Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing. 1st ed. 2012

種類:
電子ブック
責任表示:
edited by Charles E. Samuel
出版情報:
Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012
著者名:
シリーズ名:
Current Topics in Microbiology and Immunology ; 353
ISBN:
9783642228018 [3642228011]  CiNii Books  Calil
注記:
The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected.  It also is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins.
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