Telomeres and telomerase : methods and protocols

種類:

電子ブック

責任表示:

edited by John A. Double and Michael J. Thompson

出版情報:

Totowa, N.J. : Humana Press, ©2002

著者名:

• Double, John A.
• Thompson, Michael J.

シリーズ名:

Methods in molecular biology ; ; v. 191

ISBN:

9780585404882 [0585404887]    
9781592591893 [1592591892]    
9780896036574 [089603657X]    

注記:

The discovery of telomerase expression in a majority of tumors and the recognition of its potential role in the aging process has dramatically raised its profile as a target for therapeutic intervention. In Telomeres and Telomerase: Methods and Protocols, John A. Double and Michael J. Thompson have collected a critically important series of novel and essential techniques for studying telomeres and telomerase. These readily reproducible protocols provide cutting-edge tools to identify, measure, and analyze telomeres, to determine telomerase expression at the RNA level, to determine telomerase activity, and to detect potential modifiers of this activity. The techniques for assaying telomerase activity range from standard radiological TRAP assays to nonradioactive methods, from non-PCR-based methods to techniques using real-time PCR. Written by investigators who have used the methods extensively, each protocol includes step-by-step instructions, tips on avoiding pitfalls, and invaluable notes that make all the d
Includes bibliographical references and index
Print version record

ローカル注記:

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