Nuclease methods and protocols

種類:

電子ブック

責任表示:

edited by Catherine H. Schein

出版情報:

Totowa, NJ : Humana Press, ©2001

著者名:

Schein, Catherine H.  

シリーズ名:

Methods in molecular biology ; ; v. 160

ISBN:

9781592592333 [1592592333]    
9780896036796 [0896036790]    
9780585403281 [0585403287]    
9781280830365 [1280830360]    
9786610830367 [6610830363]    

注記:

Nucleases, the enzymes that cleave and shape nucleic acids, are key regulators of cellular metabolism. Angiogenesis and the unfolded protein response are just a few instances of important intra- and extracellular pathways regulated by nucleases. In Nuclease Methods and Protocols, researchers at the forefront of academic research and pharmaceutical drug development from four continents summarize their recent results. Their projects involve nucleases in many different areas of medicine and biology, ranging from protein structure and folding, to DNA repair, to developing cures for insidious diseases such as cystic fibrosis, AIDS, and cancer. Each chapter contains a minireview of a specific nuclease or nuclease-related theme, a discussion of why and when to use the assays described, and often, an explanation of how the assay was developed. The authors describe their most valuable methods for determining the mode of action, structure, interaction with other molecules, and physiological role of nucleases. Detailed
English
Includes bibliographical references and index

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