Diversity-oriented synthesis : basics and applications in organic synthesis, drug discovery, and chemical biology

種類:

電子ブック

責任表示:

edited by Andrea Trabocchi

出版情報:

2013

著者名:

Trabocchi, Andrea.  

ISBN:

9781118618141 [1118618149]    
9781118617946 [1118617940]    
9781118618073 [1118618076]    
9781118618110 [1118618114]    
9781299732568 [1299732569]    
9781118145654 [1118145658]    

注記:

"This book overviews diversity-oriented synthesis (DOS), one of the leading and dynamic topics in organic chemistry and drug discovery"-- Provided by publisher.
Includes bibliographical references and index.
Machine generated contents note: Foreword Stuart L. Schreiber Preface List of Contributors Abbreviations 1 The Basics of Diversity-Oriented Synthesis Kieron M.G. O'Connell, Warren R.J.D. Galloway and David R. Spring 1.1 Introduction 1.2 What is Diversity-Oriented Synthesis? 1.3 Small Molecules and Biology 1.4 Comparing DOS, TOS and Combinatorial Chemistry (Focused Library Synthesis) 1.5 Molecular Diversity 1.6 Molecular Diversity and Chemical Space 1.7 Synthetic Strategies for Creating Molecular Diversity 1.8 Reagent-Based Approaches to Diversity Generation 1.9 A Substrate-Based Approach to Skeletal Diversity Generation 1.10 Other Build/Couple/Pair Examples 1.11 Concluding Remarks 1.12 References Part I Chemical Methodology in Diversity-Oriented Synthesis 2 Strategies Applications of Multicomponent Reactions (MCRs) to Diversity-Oriented Synthesis John M. Knapp, Mark J. Kurth, Jared T. Shaw and Ashkaan Younai 2.1 Introduction 2.2 MCR Products for HTS 2.3 MCRs as Starting Points for DOS 2.4 Conclusion 2.5 Refer
Print version record and CIP data provided by publisher.

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